Evidence for type III restriction and modification systems in Mycoplasma pulmonis.

ABSTRACT: Mycoplasma pulmonis possesses a cassette of genes that are predicted to code for type III restriction and modification (R-M) enzymes. Transposon disruption of a gene predicted to code for the endonuclease subunit of the enzyme resulted in loss of R-M activity. Genomic data indicate that the cassette was acquired by horizontal gene transfer and possibly located on a mobile element.

SUBMITTER: Dybvig K 

PROVIDER: S-EPMC1899405 | biostudies-literature | 2007 Mar

REPOSITORIES: biostudies-literature