MASPECTRAS: a platform for management and analysis of proteomics LC-MS/MS data.

ABSTRACT:

Background

The advancements of proteomics technologies have led to a rapid increase in the number, size and rate at which datasets are generated. Managing and extracting valuable information from such datasets requires the use of data management platforms and computational approaches.

Results

We have developed the MAss SPECTRometry Analysis System (MASPECTRAS), a platform for management and analysis of proteomics LC-MS/MS data. MASPECTRAS is based on the Proteome Experimental Data Repository (PEDRo) relational database schema and follows the guidelines of the Proteomics Standards Initiative (PSI). Analysis modules include: 1) import and parsing of the results from the search engines SEQUEST, Mascot, Spectrum Mill, X! Tandem, and OMSSA; 2) peptide validation, 3) clustering of

SUBMITTER: Hartler J 

PROVIDER: S-EPMC1906842 | biostudies-literature | 2007 Jun

REPOSITORIES: biostudies-literature