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Fluorescent CXCR4 chemokine receptor antagonists: metal activated binding.

ABSTRACT: The copper(II) complex of a novel rhodamine-azamacrocycle conjugate binds to the CXCR4 chemokine receptor and competes effectively against anti-CXCR4 monoclonal antibodies. The copper macrocycle unit adopts a trans-II configuration in the solid state.

SUBMITTER: Khan A 

PROVIDER: S-EPMC1913474 | biostudies-literature |

REPOSITORIES: biostudies-literature

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