Profiling of chicken adipose tissue gene expression by genome array.

ABSTRACT:

Background

Excessive accumulation of lipids in the adipose tissue is a major problem in the present-day broiler industry. However, few studies have analyzed the expression of adipose tissue genes that are involved in pathways and mechanisms leading to adiposity in chickens. Gene expression profiling of chicken adipose tissue could provide key information about the ontogenesis of fatness and clarify the molecular mechanisms underlying obesity. In this study, Chicken Genome Arrays were used to construct an adipose tissue gene expression profile of 7-week-old broilers, and to screen adipose tissue genes that are differentially expressed in lean and fat lines divergently selected over eight generations for high and low abdominal fat weight.

Results

The gene expression profiles d

SUBMITTER: Wang HB 

PROVIDER: S-EPMC1914355 | biostudies-literature | 2007 Jun

REPOSITORIES: biostudies-literature