Hydrophobic, hydrophilic, and charged amino acid networks within protein.

ABSTRACT: The native three-dimensional structure of a single protein is determined by the physicochemical nature of its constituent amino acids. The 20 different types of amino acids, depending on their physicochemical properties, can be grouped into three major classes: hydrophobic, hydrophilic, and charged. The anatomy of the weighted and unweighted networks of hydrophobic, hydrophilic, and charged residues separately for a large number of proteins were studied. Results showed that the average degree of the hydrophobic networks has a significantly larger value than that of hydrophilic and charged networks. The average degree of the hydrophilic networks is slightly higher than that of the charged networks. The average strength of the nodes of hydrophobic networks is nearly equal to that of the char

SUBMITTER: Aftabuddin M 

PROVIDER: S-EPMC1914426 | biostudies-literature | 2007 Jul

REPOSITORIES: biostudies-literature