Novel base catalysed rearrangement of sultone oximes to 1,2-benzisoxazole-3-methane sulfonate derivatives.

ABSTRACT: A new process for the preparation of 1,2-benzisoxazole-3-methanesulfonates and 4-oximino-2,3-dihydrobenzoxathiin-2,2-dioxides (sultone oximes) is described. These compounds are important intermediates for the preparation of zonisamide, an anti-convulsant drug.

SUBMITTER: Arava VR 

PROVIDER: S-EPMC1919382 | biostudies-literature | 2007 Jun

REPOSITORIES: biostudies-literature