ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins.

ABSTRACT: A major problem in structural biology is the recognition of errors in experimental and theoretical models of protein structures. The ProSA program (Protein Structure Analysis) is an established tool which has a large user base and is frequently employed in the refinement and validation of experimental protein structures and in structure prediction and modeling. The analysis of protein structures is generally a difficult and cumbersome exercise. The new service presented here is a straightforward and easy to use extension of the classic ProSA program which exploits the advantages of interactive web-based applications for the display of scores and energy plots that highlight potential problems spotted in protein structures. In particular, the quality scores of a protein are displayed in the

SUBMITTER: Wiederstein M 

PROVIDER: S-EPMC1933241 | biostudies-literature | 2007 Jul

REPOSITORIES: biostudies-literature