Adaptation in bacterial flagellar and motility systems: from regulon members to 'foraging'-like behavior in E. coli.

ABSTRACT: Bacterial flagellar motility and chemotaxis help cells to reach the most favorable environments and to successfully compete with other micro-organisms in response to external stimuli. Escherichia coli is a motile gram-negative bacterium, and the flagellar regulon in E. coli is controlled by a master regulator FlhDC as well as a second regulator, flagellum-specific sigma factor, sigma(F). To define the physiological role of these two regulators, we carried out transcription profiling experiments to identify, on a genome-wide basis, genes under the control of these two regulators. In addition, the synchronized pattern of increasing CRP activity causing increasing FlhDC expression with decreasing carbon source quality, together with the apparent coupling of motility activity with the activati

SUBMITTER: Zhao K 

PROVIDER: S-EPMC1935009 | biostudies-literature | 2007

REPOSITORIES: biostudies-literature