Use of multiplex PCR to identify Staphylococcus aureus adhesins involved in human hematogenous infections.

ABSTRACT: We have developed a multiplex PCR procedure to determine the distribution of nine adhesin genes in Staphylococcus aureus isolates. Only genes encoding bone sialoprotein binding protein and fibronectin binding protein B were significantly associated with hematogenous osteomyelitis/arthritis and native-valve endocarditis, respectively, suggesting their involvement in hematogenous tissue infections.

SUBMITTER: Tristan A 

PROVIDER: S-EPMC193818 | biostudies-literature | 2003 Sep

REPOSITORIES: biostudies-literature