Differential recognition of Plasmodium falciparum merozoite surface protein 2 variants by antibodies from malaria patients in Brazil.

ABSTRACT: Four variants of merozoite surface protein 2 (MSP-2) of Plasmodium falciparum were used in serology to examine whether changes in repeat units affect its recognition by antibodies during infection with parasites of known MSP-2 types. The results indicate that variation in MSP-2 repeats may represent a mechanism for parasite immune evasion.

SUBMITTER: Kanunfre KA 

PROVIDER: S-EPMC193907 | biostudies-literature | 2003 Sep

REPOSITORIES: biostudies-literature