Sterility and gene expression in hybrid males of Xenopus laevis and X. muelleri.

ABSTRACT:

Background

Reproductive isolation is a defining characteristic of populations that represent unique biological species, yet we know very little about the gene expression basis for reproductive isolation. The advent of powerful molecular biology tools provides the ability to identify genes involved in reproductive isolation and focuses attention on the molecular mechanisms that separate biological species. Herein we quantify the sterility pattern of hybrid males in African Clawed Frogs (Xenopus) and apply microarray analysis of the expression pattern found in testes to identify genes that are misexpressed in hybrid males relative to their two parental species (Xenopus laevis and X. muelleri).

Methodology/principal findings

Phenotypic characteristics of spermatogenesis in ster

SUBMITTER: Malone JH 

PROVIDER: S-EPMC1940320 | biostudies-literature | 2007 Aug

REPOSITORIES: biostudies-literature