Gabapentin and postoperative pain: a qualitative and quantitative systematic review, with focus on procedure.

ABSTRACT:

Background

Gabapentin is an antiepileptic drug used in a variety of chronic pain conditions. Increasing numbers of randomized trials indicate that gabapentin is effective as a postoperative analgesic. This procedure-specific systematic review aims to analyse the 24-hour postoperative effect of gabapentin on acute pain in adults.

Methods

Medline, The Cochrane Library and Google Scholar were searched for double-blind randomized placebo controlled trials of gabapentin for postoperative pain relief compared with placebo, in adults undergoing a surgical procedure. Qualitative analysis of postoperative effectiveness was evaluated by assessment of significant difference (P < 0.05) in pain relief using consumption of supplemental analgesic and pain scores between study groups. Quant

SUBMITTER: Mathiesen O 

PROVIDER: S-EPMC1950698 | biostudies-literature | 2007 Jul

REPOSITORIES: biostudies-literature