Ontology highlight
ABSTRACT:
SUBMITTER: Anthony RM
PROVIDER: S-EPMC1955764 | biostudies-literature | 2006 Aug
REPOSITORIES: biostudies-literature
Nature medicine 20060730 8
Although primary and memory responses against bacteria and viruses have been studied extensively, T helper type 2 (T(H)2) effector mechanisms leading to host protection against helminthic parasites remain elusive. Examination of the intestinal epithelial submucosa of mice after primary and secondary infections by a natural gastrointestinal parasite revealed a distinct immune-cell infiltrate after challenge, featuring interleukin-4-expressing memory CD4(+) T cells that induced IL-4 receptor(hi) ( ...[more]