Gamma oscillations dynamically couple hippocampal CA3 and CA1 regions during memory task performance.

ABSTRACT: The hippocampal formation is believed to be critical for the encoding, consolidation, and retrieval of episodic memories. Yet, how these processes are supported by the anatomically diverse hippocampal networks is still unknown. To examine this issue, we tested rats in a hippocampus-dependent delayed spatial alternation task on a modified T maze while simultaneously recording local field potentials from dendritic and somatic layers of the dentate gyrus, CA3, and CA1 regions by using high-density, 96-site silicon probes. Both the power and coherence of gamma oscillations exhibited layer-specific changes during task performance. Peak increases in the gamma power and coherence were found in the CA3-CA1 interface on the maze segment approaching the T junction, independent of motor aspects of ta

SUBMITTER: Montgomery SM 

PROVIDER: S-EPMC1964875 | biostudies-literature | 2007 Sep

REPOSITORIES: biostudies-literature