Direct selection on genetic robustness revealed in the yeast transcriptome.

ABSTRACT:

Background

Evolutionary theory predicts that organisms should evolve the ability to produce high fitness phenotypes in the face of environmental disturbances (environmental robustness) or genetic mutations (genetic robustness). While several studies have uncovered mechanisms that lead to both environmental and genetic robustness, we have yet to understand why some components of the genome are more robust than others. According to evolutionary theory, environmental and genetic robustness will have different responses to selective forces. Selection on environmental robustness for a trait is expected to be strong and related to the fitness costs of altering that trait. In contrast to environmental robustness, selection on genetic robustness for a trait is expected to be largely indepe

SUBMITTER: Proulx SR 

PROVIDER: S-EPMC1975671 | biostudies-literature | 2007 Sep

REPOSITORIES: biostudies-literature