Effect of lung volume reduction surgery on resting pulmonary hemodynamics in severe emphysema.

ABSTRACT:

Rationale

To determine the effect of medical treatment versus lung volume reduction surgery (LVRS) on pulmonary hemodynamics.

Methods

Three clinical centers of the National Emphysema Treatment Trial (NETT) screened patients for additional inclusion into a cardiovascular (CV) substudy. Demographics were determined, and lung function testing, six-minute-walk distance, and maximum cardiopulmonary exercise testing were done at baseline and 6 months after medical therapy or LVRS. CV substudy patients underwent right heart catheterization at rest prerandomization (baseline) and 6 months after treatment.

Measurements and main results

A total of 110 of the 163 patients evaluated for the CV substudy were randomized in NETT (53 were ineligible), 54 to medical treatment and 56 t

SUBMITTER: Criner GJ 

PROVIDER: S-EPMC1994220 | biostudies-literature | 2007 Aug

REPOSITORIES: biostudies-literature