Impaired familiarity with preserved recollection after anterior temporal-lobe resection that spares the hippocampus.

ABSTRACT: It is well established that the medial-temporal lobe (MTL) is critical for recognition memory. The MTL is known to be composed of distinct structures that are organized in a hierarchical manner. At present, it remains controversial whether lower structures in this hierarchy, such as perirhinal cortex, support memory functions that are distinct from those of higher structures, in particular the hippocampus. Perirhinal cortex has been proposed to play a specific role in the assessment of familiarity during recognition, which can be distinguished from the selective contributions of the hippocampus to the recollection of episodic detail. Some researchers have argued, however, that the distinction between familiarity and recollection cannot capture functional specialization within the MTL and h

SUBMITTER: Bowles B 

PROVIDER: S-EPMC1995093 | biostudies-literature | 2007 Oct

REPOSITORIES: biostudies-literature