Naturally occurring and stress induced tubular structures from mammalian cells, a survival mechanism.

ABSTRACT:

Background

Tubular shaped mammalian cells in response to dehydration have not been previously reported. This may be due to the invisibility of these cells in aqueous solution, and because sugars and salts added to the cell culture for manipulation of the osmotic conditions inhibit transformation of normal cells into tubular shaped structures.

Results

We report the transformation of normal spherical mammalian cells into tubular shaped structures in response to stress. We have termed these transformed structures 'straw cells' which we have associated with a variety of human tissue types, including fresh, post mortem and frozen lung, liver, skin, and heart. We have also documented the presence of straw cells in bovine brain and prostate tissues of mice. The number of straw cell

SUBMITTER: Wu Y 

PROVIDER: S-EPMC2000880 | biostudies-literature | 2007 Aug

REPOSITORIES: biostudies-literature