The Edinburgh human metabolic network reconstruction and its functional analysis.
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ABSTRACT:
SUBMITTER: Ma H
PROVIDER: S-EPMC2013923 | biostudies-literature | 2007
REPOSITORIES: biostudies-literature
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The Edinburgh human metabolic network reconstruction and its functional analysis.
Ma Hongwu H Sorokin Anatoly A Mazein Alexander A Selkov Alex A Selkov Evgeni E Demin Oleg O Goryanin Igor I
Molecular systems biology 20070918
A better understanding of human metabolism and its relationship with diseases is an important task in human systems biology studies. In this paper, we present a high-quality human metabolic network manually reconstructed by integrating genome annotation information from different databases and metabolic reaction information from literature. The network contains nearly 3000 metabolic reactions, which were reorganized into about 70 human-specific metabolic pathways according to their functional re ...[more]
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