PROUD: effects of preoperative long-term immunonutrition in patients listed for liver transplantation.

ABSTRACT:

Background

Patients with end stage liver disease are characteristically malnourished which is associated with poor outcome. Formulas enriched with arginine, omega-3 fatty acids, and nucleotides, "immunonutrients", potentially improve their nutritional status. This study is designed to evaluate the clinical outcome of long-term "immunonutrition" of patients with end-stage liver disease while on the waiting list for liver transplantation.

Methods/design

A randomized controlled double blind multi-center clinical trial with two parallel groups comprising a total of 142 newly registered patients for primary liver transplantation has been designed to assess the safety and efficacy of the long-term administration of ORAL IMPACT, an "immunonutrient" formula, while waiting for a graf

SUBMITTER: Nickkholgh A 

PROVIDER: S-EPMC2018725 | biostudies-literature | 2007 Aug

REPOSITORIES: biostudies-literature