A virtual look at Epstein-Barr virus infection: biological interpretations.

ABSTRACT: The possibility of using computer simulation and mathematical modeling to gain insight into biological and other complex systems is receiving increased attention. However, it is as yet unclear to what extent these techniques will provide useful biological insights or even what the best approach is. Epstein-Barr virus (EBV) provides a good candidate to address these issues. It persistently infects most humans and is associated with several important diseases. In addition, a detailed biological model has been developed that provides an intricate understanding of EBV infection in the naturally infected human host and accounts for most of the virus' diverse and peculiar properties. We have developed an agent-based computer model/simulation (PathSim, Pathogen Simulation) of this biological mode

SUBMITTER: Duca KA 

PROVIDER: S-EPMC2034398 | biostudies-literature | 2007 Oct

REPOSITORIES: biostudies-literature