Sleep-related hippocampo-cortical interplay during emotional memory recollection.

ABSTRACT: Emotional events are usually better remembered than neutral ones. This effect is mediated in part by a modulation of the hippocampus by the amygdala. Sleep plays a role in the consolidation of declarative memory. We examined the impact of sleep and lack of sleep on the consolidation of emotional (negative and positive) memories at the macroscopic systems level. Using functional MRI (fMRI), we compared the neural correlates of successful recollection by humans of emotional and neutral stimuli, 72 h after encoding, with or without total sleep deprivation during the first post-encoding night. In contrast to recollection of neutral and positive stimuli, which was deteriorated by sleep deprivation, similar recollection levels were achieved for negative stimuli in both groups. Successful recolle

SUBMITTER: Sterpenich V 

PROVIDER: S-EPMC2039770 | biostudies-literature | 2007 Oct

REPOSITORIES: biostudies-literature