The microtubule-associated protein doublecortin is broadly expressed in the telencephalon of adult canaries.

ABSTRACT: The protein doublecortin (DCX) is expressed in post-mitotic migrating and differentiating neurons in the developing vertebrate brain and, as a part of the microtubule machinery, is required for neuronal migration. DCX expression is generally maximal during embryonic and early post-natal life but decreases markedly and almost disappears in older animals in parallel with the major decrease or cessation of neurogenesis. In several seasonally breeding songbird species such as canaries, the volume of several song control nuclei in the brain varies seasonally such that the largest nuclei are observed in the late spring and early summer. This variation is based on changes in cell size, dendritic branching, and, in nucleus HVC, on the incorporation of neurons newly born in adulthood. Because songb

SUBMITTER: Boseret G 

PROVIDER: S-EPMC2040224 | biostudies-literature | 2007 May

REPOSITORIES: biostudies-literature