Emergence of a virulent clade of Vibrio vulnificus and correlation with the presence of a 33-kilobase genomic island.

ABSTRACT: Vibrio vulnificus is a ubiquitous inhabitant of the marine coastal environment, and an important pathogen of humans. We characterized a globally distributed sample of environmental isolates from a range of habitats and hosts and compared these with isolates recovered from cases of human infection. Multilocus sequence typing data using six housekeeping genes divided 63 of the 67 isolates into the two main lineages previously noted for this species, and this division was also confirmed using the 16S rRNA and open reading frame VV0401 markers. Lineage I was comprised exclusively of biotype 1 isolates, whereas lineage II contained biotype 1 and all biotype 2 isolates. Four isolates did not cluster within either lineage: two biotype 3 and two biotype 1 isolates. The proportion of isolates recov

SUBMITTER: Cohen AL 

PROVIDER: S-EPMC2042058 | biostudies-literature | 2007 Sep

REPOSITORIES: biostudies-literature