Ontology highlight
ABSTRACT:
SUBMITTER: Govin J
PROVIDER: S-EPMC2063955 | biostudies-literature | 2007 Jan
REPOSITORIES: biostudies-literature
The Journal of cell biology 20070101 3
During male germ cell postmeiotic maturation, dramatic chromatin reorganization occurs, which is driven by completely unknown mechanisms. For the first time, we describe a specific reprogramming of mouse pericentric heterochromatin. Initiated when histones undergo global acetylation in early elongating spermatids, this process leads to the establishment of new DNA packaging structures organizing the pericentric regions in condensing spermatids. Five new histone variants were discovered, which ar ...[more]