Reappraisal of Vipera aspis venom neurotoxicity.

ABSTRACT:

Background

The variation of venom composition with geography is an important aspect of intraspecific variability in the Vipera genus, although causes of this variability remain unclear. The diversity of snake venom is important both for our understanding of venomous snake evolution and for the preparation of relevant antivenoms to treat envenomations. A geographic intraspecific variation in snake venom composition was recently reported for Vipera aspis aspis venom in France. Since 1992, cases of human envenomation after Vipera aspis aspis bites in south-east France involving unexpected neurological signs were regularly reported. The presence of genes encoding PLA(2) neurotoxins in the Vaa snake genome led us to investigate any neurological symptom associated with snake bites in oth

SUBMITTER: Ferquel E 

PROVIDER: S-EPMC2065900 | biostudies-literature | 2007 Nov

REPOSITORIES: biostudies-literature