A mixture of prebiotic oligosaccharides reduces the incidence of atopic dermatitis during the first six months of age.

ABSTRACT:

Background

Oligosaccharides may alter postnatal immune development by influencing the constitution of gastrointestinal bacterial flora.

Aims

To investigate the effect of a prebiotic mixture of galacto- and long chain fructo-oligosaccharides on the incidence of atopic dermatitis (AD) during the first six months of life in formula fed infants at high risk of atopy.

Methods

Prospective, double-blind, randomised, placebo controlled trial; 259 infants at risk for atopy were enrolled. A total of 102 infants in the prebiotic group and 104 infants in the placebo group completed the study. If bottle feeding was started, the infant was randomly assigned to one of two hydrolysed protein formula groups (0.8 g/100 ml prebiotics or maltodextrine as placebo). All infants were examin

SUBMITTER: Moro G 

PROVIDER: S-EPMC2066015 | biostudies-literature | 2006 Oct

REPOSITORIES: biostudies-literature