Hypotonic versus isotonic saline in hospitalised children: a systematic review.

ABSTRACT:

Background

The traditional recommendations which suggest that hypotonic intravenous (i.v.) maintenance fluids are the solutions of choice in paediatric patients have not been rigorously tested in clinical trials, and may not be appropriate for all children.

Aims

To systematically review the evidence from studies evaluating the safety of administering hypotonic versus isotonic i.v. maintenance fluids in hospitalised children.

Methods

Data sources

Medline (1966-2006), Embase (1980-2006), the Cochrane Library, abstract proceedings, personal files, and reference lists. Studies that compared hypotonic to isotonic maintenance solutions in children were selected. Case reports and studies in neonates or patients with a pre-existing history of hyponatraemia were exclud

SUBMITTER: Choong K 

PROVIDER: S-EPMC2066024 | biostudies-literature | 2006 Oct

REPOSITORIES: biostudies-literature