A hybrid microfluidic-vacuum device for direct interfacing with conventional cell culture methods.

ABSTRACT:

Background

Microfluidics is an enabling technology with a number of advantages over traditional tissue culture methods when precise control of cellular microenvironment is required. However, there are a number of practical and technical limitations that impede wider implementation in routine biomedical research. Specialized equipment and protocols required for fabrication and setting up microfluidic experiments present hurdles for routine use by most biology laboratories.

Results

We have developed and validated a novel microfluidic device that can directly interface with conventional tissue culture methods to generate and maintain controlled soluble environments in a Petri dish. It incorporates separate sets of fluidic channels and vacuum networks on a single device that all

SUBMITTER: Chung BG 

PROVIDER: S-EPMC2071914 | biostudies-literature | 2007 Sep

REPOSITORIES: biostudies-literature