Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis.

ABSTRACT:

Objective

To quantify the risk of future cardiovascular diseases, cancer, and mortality after pre-eclampsia.

Design

Systematic review and meta-analysis.

Data sources

Embase and Medline without language restrictions, including papers published between 1960 and December 2006, and hand searching of reference lists of relevant articles and reviews for additional reports.

Review methods

Prospective and retrospective cohort studies were included, providing a dataset of 3,488,160 women, with 198,252 affected by pre-eclampsia (exposure group) and 29,495 episodes of cardiovascular disease and cancer (study outcomes).

Results

After pre-eclampsia women have an increased risk of vascular disease. The relative risks (95% confidence intervals) for hypertension were 3.

SUBMITTER: Bellamy L 

PROVIDER: S-EPMC2072042 | biostudies-literature | 2007 Nov

REPOSITORIES: biostudies-literature