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AMPK and SNF1: Snuffing Out Stress.


ABSTRACT: AMP-activated protein kinase (AMPK) has attracted much attention for its key role in energy homeostasis. Three new papers providing structural information on mammalian and yeast AMPK homologs give insights into the binding of the regulatory nucleotides AMP and ATP and how mutations are associated with cardiac glycogen storage disorders.

SUBMITTER: Hardie DG 

PROVIDER: S-EPMC2080653 | biostudies-literature | 2007 Nov

REPOSITORIES: biostudies-literature

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AMPK and SNF1: Snuffing Out Stress.

Hardie D Grahame DG  

Cell metabolism 20071101 5


AMP-activated protein kinase (AMPK) has attracted much attention for its key role in energy homeostasis. Three new papers providing structural information on mammalian and yeast AMPK homologs give insights into the binding of the regulatory nucleotides AMP and ATP and how mutations are associated with cardiac glycogen storage disorders. ...[more]

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