New analysis for consistency among markers in the study of genetic diversity: development and application to the description of bacterial diversity.

ABSTRACT:

Background

The development of post-genomic methods has dramatically increased the amount of qualitative and quantitative data available to understand how ecological complexity is shaped. Yet, new statistical tools are needed to use these data efficiently. In support of sequence analysis, diversity indices were developed to take into account both the relative frequencies of alleles and their genetic divergence. Furthermore, a method for describing inter-population nucleotide diversity has recently been proposed and named the double principal coordinate analysis (DPCoA), but this procedure can only be used with one locus. In order to tackle the problem of measuring and describing nucleotide diversity with more than one locus, we developed three versions of multiple DPCoA by using thr

SUBMITTER: Pavoine S 

PROVIDER: S-EPMC2082430 | biostudies-literature | 2007 Sep

REPOSITORIES: biostudies-literature