Rapid T cell receptor-mediated SHP-1 S591 phosphorylation regulates SHP-1 cellular localization and phosphatase activity.

ABSTRACT: Since the tyrosine phosphatase SHP-1 plays a major role in regulating T cell signaling, we investigated regulation thereof by Ser/Thr phosphorylation. We found that T cell receptor (TCR) stimulation induced fast (

SUBMITTER: Liu Y 

PROVIDER: S-EPMC2084461 | biostudies-literature | 2007 Sep

REPOSITORIES: biostudies-literature