Systemic inflammation and lung function in young adults.

ABSTRACT:

Background

Impaired lung function is associated with systemic inflammation and is a risk factor for cardiovascular disease in older adults. It is unknown when these associations emerge and to what extent they are mediated by smoking, chronic airways disease, and/or established atherosclerosis. We explored the association between the forced expiratory volume in one second (FEV(1)) and the systemic inflammatory marker C-reactive protein (CRP) in young adults.

Methods

Associations between spirometric lung function and blood CRP were assessed in a population based birth cohort of approximately 1000 New Zealanders at ages 26 and 32 years. Analyses adjusted for height and sex to account for differences in predicted lung function and excluded pregnant women.

Results

There we

SUBMITTER: Hancox RJ 

PROVIDER: S-EPMC2094275 | biostudies-literature | 2007 Dec

REPOSITORIES: biostudies-literature