Dynamics of learning in cultured neuronal networks with antagonists of glutamate receptors.

ABSTRACT: Cognitive dysfunction may result from abnormality of ionotropic glutamate receptors. Although various forms of synaptic plasticity in learning that rely on altering of glutamate receptors have been considered, the evidence is insufficient from an informatics view. Dynamics could reflect neuroinformatics encoding, including temporal pattern encoding, spatial pattern encoding, and energy distribution. Discovering informatics encoding is fundamental and crucial to understanding the working principle of the neural system. In this article, we analyzed the dynamic characteristics of response activities during learning training in cultured hippocampal networks under normal and abnormal conditions of ionotropic glutamate receptors, respectively. The rate, which is one of the temporal configuration

SUBMITTER: Li Y 

PROVIDER: S-EPMC2098743 | biostudies-literature | 2007 Dec

REPOSITORIES: biostudies-literature