Non-tuberculous mycobacteria in end stage cystic fibrosis: implications for lung transplantation.

ABSTRACT:

Background

WC and NS contributed equally. Non-tuberculous mycobacteria (NTM) frequently colonise patients with end stage cystic fibrosis (CF), but its impact on the course of the disease following lung transplantation is unknown.

Methods

Lung transplant recipients with CF who underwent lung transplantation at our institution between January 1990 and May 2003 (n=146) and CF patients awaiting lung transplantation in May 2003 (n=31) were studied retrospectively.

Results

The prevalence rate of NTM isolated from respiratory cultures in patients with end stage CF referred for lung transplantation was 19.7%, compared with a prevalence rate of 13.7% for NTM isolates in CF lung transplant recipients. The overall prevalence of invasive NTM disease after lung transplantation was

SUBMITTER: Chalermskulrat W 

PROVIDER: S-EPMC2111233 | biostudies-literature | 2006 Jun

REPOSITORIES: biostudies-literature