Nasal CPAP reduces systemic blood pressure in patients with obstructive sleep apnoea and mild sleepiness.

ABSTRACT:

Background

A randomised controlled study was undertaken to examine the effect of nasal continuous positive airway pressure (CPAP) on 24 hour systemic blood pressure (BP) in patients with obstructive sleep apnoea (OSA).

Methods

Patients were fitted with an ambulatory BP measuring device as outpatients during normal activities and recorded for 24 hours before starting therapeutic or subtherapeutic (4 cm H(2)O) CPAP treatment. BP monitoring was repeated before completion of 12 weeks of treatment. The primary end point was the change in 24 hour mean BP.

Results

Twenty three of 28 participants in each treatment arm completed the study. There was no significant difference between the two groups in age, body mass index, Epworth Sleepiness Score, apnoea-hypopnoea index, arous

SUBMITTER: Hui DS 

PROVIDER: S-EPMC2117074 | biostudies-literature | 2006 Dec

REPOSITORIES: biostudies-literature