Uterine development in Turner syndrome.

ABSTRACT:

Objective

To evaluate uterine development of women with Turner syndrome (TS) receiving conventional medical care.

Study design

In a cross-sectional study we used ultrasonography for uterine evaluation in 86 women with TS 18 to 45 years of age participating in an intramural NIH study, and who had abnormal karyotypes in >70% of white blood cells. Outcomes were uterine dimensions and shape. Information on hormone treatment was obtained by personal interview.

Results

Twenty-five percent had a mature in size and shape uterus, and 31% had an immature uterus, with the remainder in a transitional category. Twenty percent of all participants were not taking hormone replacement therapy (HRT) in the preceding year. The majority on treatment were taking conjugated estrogens (CE)

SUBMITTER: Bakalov VK 

PROVIDER: S-EPMC2118059 | biostudies-literature | 2007 Nov

REPOSITORIES: biostudies-literature