Ontology highlight
ABSTRACT:
SUBMITTER: Kuo TC
PROVIDER: S-EPMC2118536 | biostudies-literature | 2007 Apr
REPOSITORIES: biostudies-literature
The Journal of experimental medicine 20070402 4
Memory B cells provide rapid protection to previously encountered antigens; however, how these cells develop from germinal center B cells is not well understood. A previously described in vitro culture system using human tonsillar germinal center B cells was used to study the transcriptional changes that occur during differentiation of human memory B cells. Kinetic studies monitoring the expression levels of several known late B cell transcription factors revealed that BCL-6 is not expressed in ...[more]