Identification of genes differentially expressed during prenatal development of skeletal muscle in two pig breeds differing in muscularity.

ABSTRACT:

Background

Postnatal muscle growth is largely depending on the number and size of muscle fibers. The number of myofibers and to a large extent their metabolic and contractile properties, which also influence their size, are determined prenatally during the process of myogenesis. Hence identification of genes and their networks governing prenatal development of skeletal muscles will provide insight into the control of muscle growth and facilitate finding the source of its variation. So far most of the genes involved in myogenesis were identified by in vitro studies using gene targeting and transgenesis. Profiling of transcriptome changes during the myogenesis in vivo promises to obtain a more complete picture. In order to address this, we performed transcriptome profiling of prenata

SUBMITTER: Murani E 

PROVIDER: S-EPMC2147030 | biostudies-literature | 2007 Oct

REPOSITORIES: biostudies-literature