Nemo: a computational tool for analyzing nematode locomotion.

ABSTRACT:

Background

The nematode Caenorhabditis elegans responds to an impressive range of chemical, mechanical and thermal stimuli and is extensively used to investigate the molecular mechanisms that mediate chemosensation, mechanotransduction and thermosensation. The main behavioral output of these responses is manifested as alterations in animal locomotion. Monitoring and examination of such alterations requires tools to capture and quantify features of nematode movement.

Results

In this paper, we introduce Nemo (nematode movement), a computationally efficient and robust two-dimensional object tracking algorithm for automated detection and analysis of C. elegans locomotion. This algorithm enables precise measurement and feature extraction of nematode movement components. In additi

SUBMITTER: Tsibidis GD 

PROVIDER: S-EPMC2148042 | biostudies-literature | 2007 Oct

REPOSITORIES: biostudies-literature