TFCONES: a database of vertebrate transcription factor-encoding genes and their associated conserved noncoding elements.

ABSTRACT:

Background

Transcription factors (TFs) regulate gene transcription and play pivotal roles in various biological processes such as development, cell cycle progression, cell differentiation and tumor suppression. Identifying cis-regulatory elements associated with TF-encoding genes is a crucial step in understanding gene regulatory networks. To this end, we have used a comparative genomics approach to identify putative cis-regulatory elements associated with TF-encoding genes in vertebrates.

Description

We have created a database named TFCONES (Transcription Factor Genes & Associated COnserved Noncoding ElementS) (http://tfcones.fugu-sg.org) which contains all human, mouse and fugu TF-encoding genes and conserved noncoding elements (CNEs) associated with them. The CNEs were id

SUBMITTER: Lee AP 

PROVIDER: S-EPMC2148067 | biostudies-literature | 2007 Nov

REPOSITORIES: biostudies-literature