New target genes controlled by the Bradyrhizobium japonicum two-component regulatory system RegSR.

ABSTRACT: RegSR-like proteins, members of the family of two-component regulatory systems, are present in a large number of proteobacteria in which they globally control gene expression mostly in a redox-responsive manner. The controlled target genes feature an enormous functional diversity. In Bradyrhizobium japonicum, the facultative root nodule symbiont of soybean, RegSR activate the transcription of the nitrogen fixation regulatory gene nifA, thus forming a RegSR-NifA cascade which is part of a complex regulatory network for gene regulation in response to changing oxygen concentrations. Whole-genome transcription profiling was performed here in order to assess the full regulatory scope of RegSR. The comparative analysis of wild-type and delta regR cells grown under oxic and microoxic conditions r

SUBMITTER: Lindemann A 

PROVIDER: S-EPMC2168637 | biostudies-literature | 2007 Dec

REPOSITORIES: biostudies-literature