Transcriptome analysis of the Vibrio fischeri LuxR-LuxI regulon.

ABSTRACT: The Vibrio fischeri quorum-sensing signal N-3-oxohexanoyl-l-homoserine lactone (3OC6-HSL) activates expression of the seven-gene luminescence operon. We used microarrays to unveil 18 additional 3OC6-HSL-controlled genes, 3 of which had been identified by other means previously. We show most of these genes are regulated by the 3OC6-HSL-responsive transcriptional regulator LuxR directly. This demonstrates that V. fischeri quorum sensing regulates a substantial number of genes other than those involved in light production.

SUBMITTER: Antunes LC 

PROVIDER: S-EPMC2168698 | biostudies-literature | 2007 Nov

REPOSITORIES: biostudies-literature