Genome sequences of two closely related Vibrio parahaemolyticus phages, VP16T and VP16C.

ABSTRACT: Two bacteriophages of an environmental isolate of Vibrio parahaemolyticus were isolated and sequenced. The VP16T and VP16C phages were separated from a mixed lysate based on plaque morphology and exhibit 73 to 88% sequence identity over about 80% of their genomes. Only about 25% of their predicted open reading frames are similar to genes with known functions in the GenBank database. Both phages have cos sites and open reading frames encoding proteins closely related to coliphage lambda's terminase protein (the large subunit). Like in coliphage lambda and other siphophages, a large operon in each phage appears to encode proteins involved in DNA packaging and capsid assembly and presumably in host lysis; we refer to this as the structural operon. In addition, both phages have open reading fr

SUBMITTER: Seguritan V 

PROVIDER: S-EPMC219397 | biostudies-literature | 2003 Nov

REPOSITORIES: biostudies-literature