Zinc supplementation in children with cholera in Bangladesh: randomised controlled trial.

ABSTRACT:

Objective

To investigate the impact of zinc supplementation in children with cholera.

Design

Double blind, randomised, placebo controlled trial.

Setting

Dhaka Hospital, Bangladesh.

Participants

179 children aged 3-14 years with watery diarrhoea and stool dark field examination positive for Vibrio cholerae and confirmed by stool culture.

Intervention

Children were randomised to receive 30 mg elemental zinc per day (n=90) or placebo (n=89) until recovery. All children received erythromycin suspension orally in a dose of 12.5 mg/kg every six hours for three days.

Main outcome measures

Duration of diarrhoea and stool output. Results 82 children in each group completed the study. More patients in the zinc group than in the control group recovered by tw

SUBMITTER: Roy SK 

PROVIDER: S-EPMC2223005 | biostudies-literature | 2008 Feb

REPOSITORIES: biostudies-literature