Comparative analysis of the sigma B-dependent stress responses in Listeria monocytogenes and Listeria innocua strains exposed to selected stress conditions.

ABSTRACT: The alternative sigma factor sigma(B) contributes to transcription of stress response and virulence genes in diverse gram-positive bacterial species. The composition and functions of the Listeria monocytogenes and Listeria innocua sigma(B) regulons were hypothesized to differ due to virulence differences between these closely related species. Transcript levels in stationary-phase cells and in cells exposed to salt stress were characterized by microarray analyses for both species. In L. monocytogenes, 168 genes were positively regulated by sigma(B); 145 of these genes were preceded by a putative sigma(B) consensus promoter. In L. innocua, 64 genes were positively regulated by sigma(B). sigma(B) contributed to acid stress survival in log-phase cells for both species but to survival in statio

SUBMITTER: Raengpradub S 

PROVIDER: S-EPMC2223194 | biostudies-literature | 2008 Jan

REPOSITORIES: biostudies-literature