Basic-zipper-type transcription factor FlbB controls asexual development in Aspergillus nidulans.

ABSTRACT: The fungal colony is a complex multicellular unit consisting of various cell types and functions. Asexual spore formation (conidiation) is integrated through sensory and regulatory elements into the general morphogenetic plan, in which the activation of the transcription factor BrlA is the first determining step. A number of early regulatory elements acting upstream of BrlA (fluG and flbA-E) have been identified, but their functional relations remain to be further investigated. In this report we describe FlbB as a putative basic-zipper-type transcription factor restricted to filamentous fungi. FlbB accumulates at the hyphal apex during early vegetative growth but is later found in apical nuclei, suggesting that an activating modification triggers nuclear import. Moreover, proper temporal a

SUBMITTER: Etxebeste O 

PROVIDER: S-EPMC2224158 | biostudies-literature | 2008 Jan

REPOSITORIES: biostudies-literature