Analysis of toxigenic Corynebacterium ulcerans strains revealing potential for false-negative real-time PCR results.

ABSTRACT: Diphtheria surveillance depends on the rapid and reliable recognition of the toxin gene in Corynebacterium diphtheriae. Real-time PCR is a rapid tool to confirm the presence of the diphtheria toxin gene (tox) in an isolate or specimen. We report that some toxigenic Corynebacterium ulcerans strains show atypical results in a real-time PCR for tox.

SUBMITTER: Cassiday PK 

PROVIDER: S-EPMC2224273 | biostudies-literature | 2008 Jan

REPOSITORIES: biostudies-literature