Hepatitis B virus genotypes circulating in Brazil: molecular characterization of genotype F isolates.

ABSTRACT:

Background

Hepatitis B virus (HBV) isolates have been classified in eight genotypes, A to H, which exhibit distinct geographical distributions. Genotypes A, D and F are predominant in Brazil, a country formed by a miscegenated population, where the proportion of individuals from Caucasian, Amerindian and African origins varies by region. Genotype F, which is the most divergent, is considered indigenous to the Americas. A systematic molecular characterization of HBV isolates from different parts of the world would be invaluable in establishing HBV evolutionary origins and dispersion patterns. A large-scale study is needed to map the region-by-region distribution of the HBV genotypes in Brazil.

Results

Genotyping by PCR-RFLP of 303 HBV isolates from HBsAg-positive blood donors

SUBMITTER: Mello FC 

PROVIDER: S-EPMC2231365 | biostudies-literature | 2007 Nov

REPOSITORIES: biostudies-literature